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Association of alcohol dehydrogenase and aldehyde dehydrogenase Polymorphism with Spontaneous Deep Intracerebral Haemorrhage in the Taiwan population.

Scientific reports - 27 Feb 2020

Huang Yu-Hua, Chang Kuo-Hsuan, Lee Yun-Shien, Chen Chiung-Mei, Chen Yi-Chun

Abstract excerpt

Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) encode essential alcohol-metabolizing enzymes. While alcohol use is associated with spontaneously deep intracerebral haemorrhage (SDICH), particularly in males, the activities and genetic variants of ADH and ALDH may affect SDICH development. This case-control study was conducted to identify the interaction of alcohol use and SDICH with five...

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Identifiers

PMID: 32107439
DOI: 10.1038/s41598-020-60567-5
PMCID: PMC7046678

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