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Article

Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent.

PloS one - 18 Nov 2009

Averette Kathleen M, Pratt Matthew R, Yang Yanan, Bassilian Sara, Whitelegge Julian P, Loo Joseph A, Muir Tom W, Bradley Kenneth A

Abstract excerpt

NOD-like receptors (NLRs) are a group of cytoplasmic molecules that recognize microbial invasion or 'danger signals'. Activation of NLRs can induce rapid caspase-1 dependent cell death termed pyroptosis, or a caspase-1 independent cell death termed pyronecrosis. Bacillus anthracis lethal toxin (L...

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Identifiers

PMID: 19924255
DOI: 10.1371/journal.pone.0007913
PMCID: PMC2775945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19924255-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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