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Intracellular recognition of pathogens and autophagy as an innate immune host defence

5 Jul 2011

Abstract excerpt

Pathogen recognition is the first and crucial step in innate immunity. Molecular families involved in the recognition of pathogens and activation of the innate immune responses in immunoreactive cells include the Toll-like receptor family in mammals and the peptidoglycan recognition protein (PGRP) family in Drosophila, which sense microorganisms in an extracellular or luminal compartment. Other emerging families...

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PMID: 21729928
DOI: 10.1093/jb/mvr083

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