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Article

Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain.

Nature - 3 Mar 2005

van Rossum Damian B, Patterson Randen L, Sharma Sumit, Barrow Roxanne K, Kornberg Michael, Gill Donald L, Snyder Solomon H

Abstract excerpt

Many ion channels are regulated by lipids, but prominent motifs for lipid binding have not been identified in most ion channels. Recently, we reported that phospholipase Cgamma1 (PLC-gamma1) binds to and regulates TRPC3 channels, components of agonist-induced Ca2+ entry into cells. This interacti...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15744307
DOI: 10.1038/nature03340

Genes

TRPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15744307-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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