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Article

Gelatin sponge model of effector recruitment: tumoricidal activity of adherent and non-adherent lymphokine-activated killer cells after culture in interleukin-2.

Journal of leukocyte biology - 1 Feb 1991

Akporiaye E T, Barbieri C A, Stewart C C, Bender J G

Abstract excerpt

This study examined the specific tumoricidal activity of lymphokine-activated killer (LAK) cells derived from tumor-infiltrating lymphocytes that prevent the growth of secondary tumors in animals harboring progressing primary tumors. A pre-implanted gelatin sponge was employed to capture infiltrating host effectors during the expression of concomitant tumor immunity. Additionally, this study compared the...

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PMID: 1991999
DOI: 10.1002/jlb.49.2.189

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