Article
Melanoma and lymphoma rejection associated with eosinophil infiltration upon intratumoral injection of dendritic and NK/LAK cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jun 2008
Capobianco Annalisa, Manfredi Angelo A, Monno Antonella, Rovere-Querini Patrizia, Rugarli Claudio
Abstract excerpt
Dendritic cells (DCs) are promising tools for tumor immunotherapy. Their efficacy in the tumor environment increases when tumor cells die as a consequence of chemo/radiotherapy or when local stimuli promoting DC maturation and function are available. Dying tumor cells could represent a source of tumor antigens, which DCs cross-present to tumor-specific T cells. The outcome of cross presentation is in turn...
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