Expansion of mucin-reactive T-helper lymphocytes from patients with colorectal cancer.

doi:10.1089/cbr.1995.10.115

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Article

Expansion of mucin-reactive T-helper lymphocytes from patients with colorectal cancer.

Cancer biotherapy - 1 Jan 1995

Kim J A, Martin E W, Morgan C J, Aldrich W, Triozzi P L

Abstract excerpt

The ability to identify and expand effector cells with reactivity against tumor-associated antigens (TAA) is critical for effective adoptive cellular therapy. The purpose of this study was to assess lymph node lymphocytes sensitized in vivo to the shed TAA TAG-72 as a potential source of cells fo...

Topics

Antigens, Neoplasm
CD4-CD8 Ratio
Colorectal Neoplasms
Cytotoxicity, Immunologic
Glycoproteins
Humans
Immunotherapy, Adoptive
Interleukin-2
Lymph Nodes
Mucins
Phenotype
RNA, Messenger
T-Lymphocytes, Helper-Inducer
Tumor Cells, Cultured

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