Article
Effects of OK-432 on in vitro secondary responses of the non-adherent cells to IL-2 and OK-432 in cancer patients without tumor burden.
Anticancer research - 1 Jan 2000
Fujieda S, Saito H, Isobe Y, Nakagawara G, Nishi O, Nagahara K, Watanabe Y, Hoshino T
Abstract excerpt
We examined the effect of OK-432 intracutaneous injection on the in vitro responses of non-adherent cells to IL-2 and OK-432, along with changes in lymphocyte subpopulations, in early cancer patients who underwent surgery. We found that 1) repeated injections of OK-432 resulted in an enhancement of LAK activity, the peak of which was seen between 7 and 10 days after the first administration, 2) this augmentation...
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