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Article

Lack of association between Toll-like receptor 4 gene polymorphisms and giant cell arteritis.

Rheumatology (Oxford, England) - 1 Sept 2011

Alvarez-Rodriguez Lorena, Lopez-Hoyos Marcos, Beares Ignacio, Muñoz Cacho Pedro, Mata Cristina, Calvo-Alen Jaime, Corrales Alfonso, Tripathi Gaurav, Blanco Ricardo, Garcia-Unzueta Maite, Villa Ignacio, Martinez-Taboada Victor M

Abstract excerpt

OBJECTIVE: Coding variants in Toll-like receptor 4 (TLR4) have been reported to be associated with inflammatory diseases. The aim of this study was to determine whether two of these polymorphisms (+896 A/G and +1196 C/T) are associated with susceptibility and clinical features of GCA. We also attempted to correlate the functional consequences of these polymorphisms. METHODS: A total of 72 patients with GCA and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21586524
DOI: 10.1093/rheumatology/ker168

Genes

TLR4
GCA

Provenance

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