Article
TLR4 polymorphism is not associated with biopsy proven giant cell arteritis.
Clinical and experimental rheumatology - 1 Jan 2000
Dunstan Emma, Lester Sue, Rischmueller Maureen, Chan Helan, Hewitt Alex W, Hill Catherine
Abstract excerpt
OBJECTIVES: Giant cell arteritis (GCA) is a systemic inflammatory vasculitis affecting the elderly. It primarily affects medium and large arteries of the head and neck and can cause stroke and blindness. The cause of GCA is unknown; however both genetic and environmental factors are likely to be involved. TLR4 is implicated in the pathogenesis of GCA, however previous studies, examining the association between...
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