Article
Molecular analysis, mutation screening, and association study of adenylate cyclase type 9 gene (ADCY9) in mood disorders.
American journal of medical genetics - 8 Jan 2002
Toyota Tomoko, Hattori Eiji, Meerabux Joanne, Yamada Kazuo, Saito Koji, Shibuya Haruo, Nankai Masahiro, Yoshikawa Takeo
Abstract excerpt
Chromosome 16p13 has been shown to display modest linkage signals for mood disorders in a number of studies. An interesting candidate gene in this region is the adenylate cyclase (AC) type 9 gene (ADCY9). ACs are critical in neuronal signaling, and perturbation of brain AC activity has been reported in mood disorder postmortem brains. ACs may also act as targets of antidepressants. Two distinct length transcripts...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
