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Article

Pituitary adenylate cyclase-activating polypeptide induces a depressive-like phenotype in rats.

Psychopharmacology - 1 Oct 2015

Seiglie Mariel P, Smith Karen L, Blasio Angelo, Cottone Pietro, Sabino Valentina

Abstract excerpt

BACKGROUND: Major depressive disorder (MDD) is a chronic, life-threatening psychiatric condition characterized by depressed mood, psychomotor alterations, and a markedly diminished interest or pleasure in most activities known as anhedonia. Available pharmacotherapies have limited success and the need for new strategies is clear. Recent studies attribute a major role to the pituitary adenylate cyclase-activating...

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Identifiers

PMID: 26264905
DOI: 10.1007/s00213-015-4045-4
PMCID: PMC4565740

Genes

FST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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