Article
Genetic polymorphisms in glutathione S-transferase (GST) superfamily and arsenic metabolism in residents of the Red River Delta, Vietnam.
Toxicology and applied pharmacology - 1 Feb 2010
Agusa Tetsuro, Iwata Hisato, Fujihara Junko, Kunito Takashi, Takeshita Haruo, Minh Tu Binh, Trang Pham Thi Kim, Viet Pham Hung, Tanabe Shinsuke
Abstract excerpt
To elucidate the role of genetic factors in arsenic metabolism, we investigated associations of genetic polymorphisms in the members of glutathione S-transferase (GST) superfamily with the arsenic concentrations in hair and urine, and urinary arsenic profile in residents in the Red River Delta, Vietnam. Genotyping was conducted for GST omega1 (GSTO1) Ala140Asp, Glu155del, Glu208Lys, Thr217Asn, and Ala236Val, GST...
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