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Article

Interactive Influence of N6AMT1 and As3MT Genetic Variations on Arsenic Metabolism in the Population of Inner Mongolia, China.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Jan 2017

Chen Xushen, Guo Xiaojuan, He Ping, Nie Jing, Yan Xiaoyan, Zhu Jinqiu, Zhang Luoping, Mao Guangyun, Wu Hongmei, Liu Zhiyue, Aga Diana, Xu Peilin, Smith Martyn, Ren Xuefeng

Abstract excerpt

Chronic arsenic exposure via drinking water has become a worldwide public health concern. In humans, inorganic arsenic (iAs) is metabolized to monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) mainly mediated by arsenic (+3 oxidation state) methyltransferase (As3MT). We reported recently that N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) was involved in arsenic metabolism, and examined its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Site-Specific DNA-Methyltransferase (Adenine-Specific)

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Identifiers

PMID: 27637898
DOI: 10.1093/toxsci/kfw181
PMCID: PMC5216648

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