Article
Individual variations in arsenic metabolism in Vietnamese: the association with arsenic exposure and GSTP1 genetic polymorphism.
Metallomics : integrated biometal science - 1 Jan 2012
Agusa Tetsuro, Kunito Takashi, Tue Nguyen Minh, Lan Vi Thi Mai, Fujihara Junko, Takeshita Haruo, Minh Tu Binh, Trang Pham Thi Kim, Takahashi Shin, Viet Pham Hung, Tanabe Shinsuke, Iwata Hisato
Abstract excerpt
We investigated the association of As exposure and genetic polymorphism in glutathione S-transferase π1 (GSTP1) with As metabolism in 190 local residents from the As contaminated groundwater areas in the Red River Delta, Vietnam. Total As concentrations in groundwater ranged from <0.1 to 502 μg l(-1). Concentrations of dimethylarsinic acid (DMA(V)), monomethylarsonic acid (MMA(V)), and arsenite (As(III)) in human...
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