Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Epiprofin, a zinc-finger transcription factor, in limb development.

Developmental biology - 15 Jan 2010

Talamillo Ana, Delgado Irene, Nakamura Takashi, de-Vega Susana, Yoshitomi Yasuo, Unda Fernando, Birchmeier Walter, Yamada Yoshihiko, Ros Maria A

Abstract excerpt

The formation and maintenance of the apical ectodermal ridge (AER) is critical for the outgrowth and patterning of the vertebrate limb. In the present work, we have investigated the role of Epiprofin (Epfn/Sp6), a member of the SP/KLF transcription factor family that is expressed in the limb ecto...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Bone Morphogenetic Protein 4
Share to Ectoderm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extremities

Share to Fibroblast Growth Factor 8

Share to Kruppel-Like Transcription Factors

Share to Wnt Proteins

Share to Zinc Fingers

Source

Open in PubMed Open full text

Identifiers

PMID: 19913006
DOI: 10.1016/j.ydbio.2009.11.007
PMCID: PMC3538143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19913006-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Epiprofin, a zinc-finger transcription factor, in limb development.PMID 19913006Read ↗

Sp8 is crucial for limb outgrowth and neuropore closure.Semantic proximity Read ↗

Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function.Semantic proximity Read ↗

Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.Semantic proximity Read ↗

FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis.Semantic proximity Read ↗

Distal limb malformations: underlying mechanisms and clinical associations.Semantic proximity Read ↗

Kruppel-like Factors in Skeletal Physiology and PathologiesSemantic proximity Read ↗

Bmp4 in limb bud mesoderm regulates digit pattern by controlling AER development.Semantic proximity Read ↗

Transcriptional profiling of Wnt3a mutants identifies Sp transcription factors as essential effectors of the Wnt/β-catenin pathway in neuromesodermal stem cells.Semantic proximity Read ↗

The Hemimelic extra toes mouse mutant: Historical perspective on unraveling mechanisms of dysmorphogenesis.Semantic proximity Read ↗

FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.Semantic proximity Read ↗

Bhlha9 regulates apical ectodermal ridge formation during limb development.Semantic proximity Read ↗

A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.