Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current evidence for the clinical use of long-chain polyunsaturated n-3 fatty acids to prevent age-related cognitive decline and Alzheimer's disease.

The journal of nutrition, health & aging - 1 Mar 2013

Dacks P A, Shineman D W, Fillit H M

Abstract excerpt

An NIH State of the Science Conference panel concluded in 2010 that insufficient evidence is available to recommend the use of any primary prevention therapy for Alzheimer's disease or cognitive decline with age. Despite the insufficient evidence, candidate therapies with varying levels of evidence for safety and efficacy are taken by the public and discussed in the media. One example is the long-chain n-3...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Availability
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognition Disorders

Share to Depression

Share to Dietary Supplements

Share to Docosahexaenoic Acids

Share to Eicosapentaenoic Acid

Share to Meta-Analysis as Topic

Source

Open in PubMed Open full text

Identifiers

PMID: 23459977
DOI: 10.1007/s12603-012-0431-3
PMCID: PMC12878945

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current evidence for the clinical use of long-chain polyunsaturated n-3 fatty acids to prevent age-related cognitive decline and Alzheimer's disease.PMID 23459977Read ↗

Omega-3 polyunsaturated fatty acids and brain health: Preclinical evidence for the prevention of neurodegenerative diseasesSemantic proximity Read ↗

Omega 3 Fatty Acids and Neurodegenerative Diseases: New Evidence in Clinical TrialsSemantic proximity Read ↗

The role of long chain omega-3 polyunsaturated fatty acids in reducing lipid peroxidation among elderly patients with mild cognitive impairment: a case-control study.Semantic proximity Read ↗

Fatty Acids, Antioxidants and Physical Activity in Brain AgingSemantic proximity Read ↗

Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms.Semantic proximity Read ↗

Dietary omega 3 polyunsaturated fatty acids and Alzheimer's disease: interaction with apolipoprotein E genotype.Semantic proximity Read ↗

Effect of dietary omega-3 fatty acid supplementation on frailty-related phenotypes in older adults: a systematic review and meta-analysis protocol.Semantic proximity Read ↗

Providing lysophosphatidylcholine-bound omega-3 fatty acids increased eicosapentaenoic acid, but not docosahexaenoic acid, in the cortex of mice with the apolipoprotein E3 or E4 allele.Semantic proximity Read ↗

A Scoping Review of Dietary Factors Conferring Risk or Protection for Cognitive Decline in APOE ε4 Carriers.Semantic proximity Read ↗

Relationship between diet and plasma long-chain n-3 PUFAs in older people: impact of apolipoprotein E genotype.Semantic proximity Read ↗

Effects of age, sex, body mass index and APOE genotype on cardiovascular biomarker response to an n-3 polyunsaturated fatty acid supplementation.Semantic proximity Read ↗

Omega-3 Fatty Acid-Type Docosahexaenoic Acid Protects against Aβ-Mediated Mitochondrial Deficits and Pathomechanisms in Alzheimer's Disease-Related Animal Model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.