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Article

Up-regulation of the type 3 ryanodine receptor is neuroprotective in the TgCRND8 mouse model of Alzheimer's disease.

Journal of neurochemistry - 1 Jan 2010

Supnet Charlene, Noonan Charmaine, Richard Kelly, Bradley John, Mayne Michael

Abstract excerpt

The cellular pathology of Alzheimer's disease is progressive and protracted leading eventually to considerable neuronal death. The underlying mechanisms of the pathology are complex but changes in the control of intracellular Ca2+ are believed to contribute to the demise of neurons. In this study...

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Source

Identifiers

PMID: 19903243
DOI: 10.1111/j.1471-4159.2009.06487.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19903243-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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