Article
Characterisation of pncA mutations in clinical Mycobacterium tuberculosis isolates in New Zealand.
Pathology - 1 Jan 2009
Pandey Sushil, Newton Sandie, Upton Arlo, Roberts Sally, Drinković Dragana
Abstract excerpt
AIMS: To describe the molecular basis of pyrazinamide (PZA) resistance among Mycobacterium tuberculosis in New Zealand, and to compare the pncA gene sequence among isolates with phenotypic (Bactec 960 and Wayne's assay) evidence of PZA resistance. METHODS: The pncA gene of 26 clinical isolates of M. tuberculosis found to be PZA resistant by phenotypic methods was sequenced. Phenotypic and genotypic data were...
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