Article
Characterisation of the pncA gene in Mycobacterium tuberculosis isolates from Gauteng, South Africa.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Oct 2001
Bishop K S, Blumberg L, Trollip A P, Smith A N, Roux L, York D F, Kiepiela P
Abstract excerpt
SETTING: The use of pyrazinamide (PZA) is important for the treatment of Mycobacterium tuberculosis as it is bactericidal to semi-dormant mycobacteria that are not affected by other drugs. The incidence of resistance to PZA and other drugs used in the treatment of M. tuberculosis is increasing in South Africa. OBJECTIVE: To characterise the pncA gene of M. tuberculosis isolates from Gauteng, South Africa, and to...
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