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Chromosome 7 and 19 Trisomy in Cultured Human Neural Progenitor Cells

28 Oct 2009

Abstract excerpt

BACKGROUND: Stem cell expansion and differentiation is the foundation of emerging cell therapy technologies. The potential applications of human neural progenitor cells (hNPCs) are wide ranging, but a normal cytogenetic profile is important to avoid the risk of tumor formation in clinical trials. FDA approved clinical trials are being planned and conducted for hNPC transplantation into the brain or spinal cord...

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PMID: 19898616
DOI: 10.1371/journal.pone.0007630

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