Accumulation of mutations and somatic selection in aging neural stem/progenitor cells.

Abstract excerpt

Genomic instability within somatic stem cells may lead to the accumulation of mutations and contribute to cancer or other age-related phenotypes. However, determining the frequency of mutations that differ among individual stem cells is difficult from whole tissue samples because each event is di...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cellular Senescence
• Share to Chromosomes
• Share to Loss of Heterozygosity