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Article

Usa1 protein facilitates substrate ubiquitylation through two separate domains.

PloS one - 29 Oct 2009

Kim Ikjin, Li Yue, Muniz Paulina, Rao Hai

Abstract excerpt

BACKGROUND: Defects in protein folding are recognized as the root of many neurodegenerative disorders. In the endoplasmic reticulum (ER), secretory proteins are subjected to a stringent quality control process to eliminate misfolded proteins by the ER-associated degradation (ERAD) pathway. A novel ERAD component Usa1 was recently identified. However, the specific role of Usa1 in ERAD remains obscure....

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Identifiers

PMID: 19898607
DOI: 10.1371/journal.pone.0007604
PMCID: PMC2764048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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