Article
Jid1 is a J-protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation.
FEBS letters - 3 Sept 2009
Bursać Dejan, Lithgow Trevor
Abstract excerpt
J-proteins are a class of molecular chaperones that serve to stimulate the activity of Hsp70s and are often located to recruit Hsp70 to a particular cellular function. Protein degradation associated with the endoplasmic reticulum (ERAD) is one such cellular process that requires Hsp70 on both faces of the endoplasmic reticulum. At least five J-proteins, including Jid1 (DnaJ protein Involved in ER-associated...
Topics
- Endoplasmic Reticulum
- HSP40 Heat-Shock Proteins
- HSP70 Heat-Shock Proteins
- Mitochondria
- Mitochondrial Proteins
- Molecular Chaperones
- Phenotype
- Protein Transport
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins