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Article

The Png1-Rad23 complex regulates glycoprotein turnover.

The Journal of cell biology - 16 Jan 2006

Kim Ikjin, Ahn Jungmi, Liu Chang, Tanabe Kaori, Apodaca Jennifer, Suzuki Tadashi, Rao Hai

Abstract excerpt

Misfolded proteins in the endoplasmic reticulum (ER) are destroyed by a pathway termed ER-associated protein degradation (ERAD). Glycans are often removed from glycosylated ERAD substrates in the cytosol before substrate degradation, which maintains the efficiency of the proteasome. Png1, a deglycosylating enzyme, has long been suspected, but not proven, to be crucial in this process. We demonstrate that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16401726
DOI: 10.1083/jcb.200507149
PMCID: PMC2063551

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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