Article
Glutathione peroxidase-2 protects from allergen-induced airway inflammation in mice.
The European respiratory journal - 1 May 2010
Dittrich A M, Meyer H-A, Krokowski M, Quarcoo D, Ahrens B, Kube S M, Witzenrath M, Esworthy R S, Chu F-F, Hamelmann E
Abstract excerpt
The aim of the present study was to identify and validate the biological significance of new genes/proteins involved in the development of allergic airway disease in a murine asthma model. Gene microarrays were used to identify genes with at least a two-fold increase in gene expression in lungs of two separate mouse strains with high and low allergic susceptibility. Validation of mRNA data was obtained by western...
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