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<i>Gpx2</i> Is an Overexpressed Gene in Rat Breast Cancers Induced by Three Different Chemical Carcinogens

1 Dec 2007

Abstract excerpt

Gene expression alterations are essential for the process of carcinogenesis. A carcinogen may have specific mechanisms for inducing tumors, which may involve inducing characteristic gene expression alterations. In this study, we attempted to identify genes crucial for mammary carcinogenesis. For this purpose, we used human c-Ha-ras proto-oncogene transgenic rats (Hras128), which are highly sensitive to mammary...

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PMID: 18056462
DOI: 10.1158/0008-5472.can-07-2226

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