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Article

Transglutaminase 2, a novel regulator of eicosanoid production in asthma revealed by genome-wide expression profiling of distinct asthma phenotypes.

PloS one - 5 Jan 2010

Hallstrand Teal S, Wurfel Mark M, Lai Ying, Ni Zhanglin, Gelb Michael H, Altemeier William A, Beyer Richard P, Aitken Moira L, Henderson William R

Abstract excerpt

BACKGROUND: A frequent manifestation of asthma, exercise-induced bronchoconstriction (EIB), occurs in 30-50% of asthmatics and is characterized by increased release of inflammatory eicosanoids. The objective of this study was to identify genes differentially expressed in EIB and to understand the...

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Source

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Identifiers

PMID: 20052409
DOI: 10.1371/journal.pone.0008583
PMCID: PMC2797392

Genes

TGM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20052409-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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