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Article

The region between the two polyprotein initiation codons of foot-and-mouth disease virus is critical for virulence in cattle.

Virology - 5 Jan 2010

Piccone Maria E, Pacheco Juan M, Pauszek Steven J, Kramer Ed, Rieder Elizabeth, Borca Manuel V, Rodriguez Luis L

Abstract excerpt

To explore the role in viral pathogenesis of the region located between the two functional AUG (inter-AUG) in foot-and-mouth disease virus (FMDV), we derived viruses containing transposon (tn) inserts from a mutagenized cDNA infectious clone of FMDV (pA24-WT). Mutant viruses containing an in-frame 57-nt transposon insertion grew at a slower rate and had a smaller plaque size phenotype than the parental virus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19896688
DOI: 10.1016/j.virol.2009.10.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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