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Article

Genetic Determinants of Altered Virulence of Type O Foot-and-Mouth Disease Virus.

Journal of virology - 17 Mar 2020

Yang Fan, Zhu Zixiang, Cao Weijun, Liu Huanan, Wei Ting, Zheng Min, Zhang Keshan, Jin Ye, He Jijun, Guo Jianhong, Liu Xiangtao, Zheng Haixue

Abstract excerpt

Under different circumstances, the alteration of several viral genes may give an evolutionary advantage to the virus to maintain its prevalence in nature. In this study, a 70-nucleotide deletion in the small fragment (S fragment) of the viral 5'-untranslated region (5'-UTR) together with one amino acid insertion in the leader protein (Lpro) that naturally occurred in several serotype O foot-and-mouth disease...

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Identifiers

PMID: 31915277
DOI: 10.1128/JVI.01657-19
PMCID: PMC7081894

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Source receipt: pubmed, retrieved 7 Sept 2026.

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