Article
Amber codon is genetically unstable in generation of premature termination codon (PTC)-harbouring Foot-and-mouth disease virus (FMDV) via genetic code expansion.
RNA biology - 1 Dec 2021
Hao Rongzeng, Ma Kun, Ru Yi, Li Dan, Song Gaoyuan, Lu Bingzhou, Liu Huanan, Li Yajun, Zhang Jiaoyan, Wu Chunping, Zhang Guicai, Hu Haitao, Luo Jianxun, Zheng Haixue
Abstract excerpt
The foot-and-mouth disease virus (FMDV) is the causative agent of FMD, a highly infectious and devastating viral disease of domestic and wild cloven-hoofed animals. FMD affects livestock and animal products' national and international trade, causing severe economic losses and social consequences. Currently, inactivated vaccines play a vital role in FMD control, but they have several limitations. The genetic code...
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