Article
Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis.
Critical care (London, England) - 1 Jan 2009
Huh Jin Won, Song Kyuyoung, Yum Jung-Sun, Hong Sang-Bum, Lim Chae-Man, Koh Younsuck
Abstract excerpt
INTRODUCTION: Individuals deficient in mannose-binding lectin (MBL), an important component of the innate immune system, show increased susceptibility to infection. We investigated whether polymorphisms in the MBL2 gene and the serum level are associated with the severity and prognosis of sepsis. METHODS: A total of 266 patients with sepsis and 398 healthy controls were enrolled. We analyzed the three single...
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