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Article

Role of Mannose-binding Lectin-2 Promoter Genetic Variants in Susceptibility to Sepsis: A Meta and Trial Sequential Analysis.

Iranian journal of allergy, asthma, and immunology - 3 Jun 2026

Shao Hongyi, Zhang Jianfeng, Wu Dayong, Zhang Xiaoyang, Hu Chunqiong

Abstract excerpt

Mannose-binding lectin (MBL) is a critical component of the innate immune system, serving a vital role in the body's initial defense against pathogens. Sepsis, a severe condition triggered by an excessive immune response to infection, has been linked to variations in the MBL2 gene that affect MBL levels and functionality. Numerous studies across various populations have examined the role of MBL-2 promoter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42437309

Genes

MBL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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