Article
Association of mannose-binding lectin polymorphisms with sepsis and fatal outcome, in patients with systemic inflammatory response syndrome.
The Journal of infectious diseases - 1 Nov 2003
Garred Peter, J Strøm Jens, Quist Lars, Taaning Ellen, Madsen Hans O
Abstract excerpt
Genetic factors may predispose critically ill patients to increased risk of developing sepsis. Mannose-binding lectin (MBL) is an important factor in innate immune defense. We investigated whether MBL gene polymorphisms causing low levels of MBL are associated with the development and progression of sepsis in adult patients in intensive care units. In 272 prospectively monitored patients with systemic...
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