Article
Polymorphisms in the mannose binding lectin-2 gene and acute respiratory distress syndrome.
Critical care medicine - 1 Jan 2007
Gong Michelle N, Zhou Wei, Williams Paige L, Thompson B Taylor, Pothier Lucille, Christiani David C
Abstract excerpt
OBJECTIVE: The variant alleles in the mannose binding lectin-2 (MBL-2) gene have been associated with MBL deficiency and increased susceptibility to sepsis. We postulate that the variant MBL-2 genotypes are associated with increased susceptibility to and mortality in acute respiratory distress syndrome (ARDS). DESIGN: Nested case-control study. SETTING: Tertiary academic medical center. PATIENTS: Two hundred and...
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