Article
Association of common polymorphisms in GLUT9 gene with gout but not with coronary artery disease in a large case-control study.
PloS one - 9 Apr 2008
Stark Klaus, Reinhard Wibke, Neureuther Katharina, Wiedmann Silke, Sedlacek Kamil, Baessler Andrea, Fischer Marcus, Weber Stefan, Kaess Bernhard, Erdmann Jeanette, Schunkert Heribert, Hengstenberg Christian
Abstract excerpt
BACKGROUND: Serum uric acid (UA) levels have recently been shown to be genetically influenced by common polymorphisms in the GLUT9 gene in two genome-wide association analyses of Italian and British populations. Elevated serum UA levels are often found in conjunction with the metabolic syndrome. Hyperuricemia is the major risk factor for gout and has been associated with increased cardiovascular morbidity and...
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