Article
Genetic association of polymorphism rs1333049 with gout.
Rheumatology (Oxford, England) - 1 Sept 2011
Wang Binbin, Meng Dongmei, Wang Jing, Liu Shiguo, Zhou Sirui, Miao Zhimin, Han Lin, Chu Nan, Zhang Kun, Ma Xu, Li Changgui
Abstract excerpt
OBJECTIVE: We suspect that genes or loci that contribute to coronary artery disease (CAD) may also play a role in the pathogenesis of gout, since hyperuricaemia leads to gout, and serum uric acid (SUA) levels are potential risk factors for CAD. The single nucleotide polymorphism (SNP) rs1333049 (C/G) on chromosome 9p21 has been implicated in previous studies to be associated with CAD. The aim of this study was to...
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