Article
Length polymorphism in heme oxygenase-1 and cardiovascular events and mortality in hemodialysis patients.
Clinical journal of the American Society of Nephrology : CJASN - 1 Oct 2013
Chen Yu-Hsin, Hung Szu-Chun, Tarng Der-Cherng
Abstract excerpt
BACKGROUND AND OBJECTIVES: Persistent inflammation and oxidative stress play a pathogenic role in the high cardiovascular morbidity and mortality of hemodialysis patients. Heme oxygenase-1 is considered to have anti-inflammatory and antioxidant properties. This study assessed the association between the length of guanosine thymidine dinucleotide repeats in the heme oxygenase-1 gene microsatellite promoter and...
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