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Article

Mitochondrial DNA injury and mortality in hemodialysis patients.

Journal of the American Society of Nephrology : JASN - 1 Jan 2009

Rao Madhumathi, Li Lijun, Demello Caren, Guo Daqing, Jaber Bertrand L, Pereira Brian J G, Balakrishnan Vaidyanathapuram S

Abstract excerpt

The role of mitochondrial injury in the pathogenesis of complications of uremia is incompletely defined, although diminished bioenergetic capacity and the accumulation of mitochondrial DNA (mtDNA) mutations have been reported. This study was undertaken to evaluate the prevalence of mtDNA injury in 180 patients who had ESRD and were enrolled into the baseline phase of the HEMO study and to relate these markers to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

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Share to Neurological and metabolic disorders

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Source

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Identifiers

PMID: 18684894
DOI: 10.1681/ASN.2007091031
PMCID: PMC2615717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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