Article
Postnatal exposure to MK801 induces selective changes in GAD67 or parvalbumin.
Experimental brain research - 1 Mar 2010
Turner Christopher Paul, DeBenedetto Danielle, Ware Emily, Stowe Robert, Lee Andrew, Swanson John, Walburg Caroline, Lambert Alexandra, Lyle Melissa, Desai Priyanka, Liu Chun
Abstract excerpt
Brain injury during the last trimester to the first 1-4 years in humans is now thought to trigger an array of intellectual and emotional problems later in life, including disorders such as schizophrenia. In adult schizophrenic brains, there is a specific loss of neurons that co-express glutamic acid decarboxylase-parvalbumin (GAD67-PV). Loss of this phenotype is thought to occur in mature animals previously...
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