Article
Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: relevance for mental disorders.
Hippocampus - 1 Apr 2014
Inta Dragos, Vogt Miriam A, Elkin Hasan, Weber Tillmann, Lima-Ojeda Juan M, Schneider Miriam, Luoni Alessia, Riva Marco A, Gertz Karen, Hellmann-Regen Julian, Kronenberg Golo, Meyer-Lindenberg Andreas, Sprengel Rolf, Gass Peter
Abstract excerpt
Adolescence is characterized by important molecular and anatomical changes with relevance for the maturation of brain circuitry and cognitive function. This time period is of critical importance in the emergence of several neuropsychiatric disorders accompanied by cognitive impairment, such as affective disorders and schizophrenia. The molecular mechanisms underlying these changes at neuronal level during this...
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