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Article

Effects of two functionally important SLCO1B1 gene polymorphisms on pharmacokinetics of atorvastatin.

Pakistan journal of pharmaceutical sciences - 1 Jul 2017

Rajput Tausif Ahmed, Naveed Abdul Khaliq, Farooqi Ziaur Rehman, Khan Shakir

Abstract excerpt

Organic anion transporter polypeptide 1B1 (OATP1B1) encoded by (SLCO1B1) gene, an uptake transporter involved in the transport of drugs and endogenous compounds and located in hepatocyte sinusoidal membrane. Objective of study was to investigate the effects of two functionally significant SNPs (388A>G and 521T>C) and their respective genotypes of SLCO1B1 gene encoding OATP1B1 on the pharmacokinetics of...

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PMID: 29039339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of two functionally important SLCO1B1 gene polymorphisms on pharmacokinetics of atorvastatin.PMID 29039339Read ↗

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