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Article

Pharmacogenetics of membrane transporters: a review of current approaches.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Sissung Tristan M, Goey Andrew K L, Ley Ariel M, Strope Jonathan D, Figg William D

Abstract excerpt

This chapter provides a review of the pharmacogenetics of membrane transporters, including ABC transporters and OATPs. Membrane transporters are heavily involved in drug disposition, by actively transporting substrate drugs between organs and tissues. As such, polymorphisms in the genes encoding these proteins may have a significant effect on the absorption, distribution, metabolism, excretion, and activity of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25150868
DOI: 10.1007/978-1-4939-0956-8_6
PMCID: PMC6388404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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