Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relationship of estrogen receptor-alpha and -beta genes with osteoarthritis of the hand.

The Journal of rheumatology - 1 Dec 2009

Wise Barton L, Demissie Serkalem, Cupples L Adrienne, Felson David T, Yang Mei, Shearman Amanda M, Aliabadi Piran, Hunter David J

Abstract excerpt

OBJECTIVE: We examined reported associations between radiographic hand osteoarthritis (OA) and single-nucleotide polymorphisms (SNP) in 2 candidate genes associated with OA in other joints: estrogen receptor alpha (ESR1) and beta (ESR2). METHODS: In 539 Framingham Offspring Study participants (49% men; mean age 61 +/- 9 yrs) joint-specific radiographic hand OA was defined as Kellgren/Lawrence (K/L) scores >or= 2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Estrogen Receptor alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor beta

Share to Gene Frequency

Share to Osteoarthritis

Share to Polymorphism, Single Nucleotide

Share to Radiography

Source

Open in PubMed Open full text

Identifiers

PMID: 19884274
DOI: 10.3899/jrheum.081208
PMCID: PMC3641579

Genes

ESR1
ESR2
PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relationship of estrogen receptor-alpha and -beta genes with osteoarthritis of the hand.PMID 19884274Read ↗

Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in estrogen receptor alpha gene with susceptibility to knee osteoarthritis: a case-control study in a Chinese Han population.Semantic proximity Read ↗

Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study.Semantic proximity Read ↗

Estrogen receptor gene polymorphism and generalized osteoarthritis.Semantic proximity Read ↗

Association between polymorphisms in the estrogen receptor alpha gene and osteoarthritis susceptibility: a meta-analysis.Semantic proximity Read ↗

Genetic influences on hand osteoarthritis in Finnish women--a replication study of candidate genes.Semantic proximity Read ↗

Adipokine genes and radiographic hand osteoarthritis in Finnish women: a cross-sectional study.Semantic proximity Read ↗

Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population.Semantic proximity Read ↗

Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women.Semantic proximity Read ↗

Association Between Polymorphisms in the Genes of Estrogen Receptors and the Presence of Temporomandibular Disorders and Chronic Arthralgia.Semantic proximity Read ↗

Genetic estrogen receptor alpha gene PvuII polymorphism in susceptibility to knee osteoarthritis in a Chinese Han population: A southern Jiangsu study.Semantic proximity Read ↗

Significant association of full-thickness rotator cuff tears and estrogen-related receptor-β (ESRRB).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.