Article
Genetic influences on hand osteoarthritis in Finnish women--a replication study of candidate genes.
PloS one - 1 Jan 2014
Hämäläinen Satu, Solovieva Svetlana, Vehmas Tapio, Luoma Katariina, Leino-Arjas Päivi, Hirvonen Ari
Abstract excerpt
OBJECTIVES: Our aims were to replicate some previously reported associations of single nucleotide polymorphisms (SNPs) in five genes (A2BP1, COG5, GDF5, HFE, ESR1) with hand osteoarthritis (OA), and to examine whether genes (BCAP29, DIO2, DUS4L, DVWA, HLA, PTGS2, PARD3B, TGFB1 and TRIB1) associated with OA at other joint sites were associated with hand OA among Finnish women. DESIGN: We examined the bilateral...
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