Article
Adipokine genes and radiographic hand osteoarthritis in Finnish women: a cross-sectional study.
Scandinavian journal of rheumatology - 1 Jan 2018
Hämäläinen S, Solovieva S, Vehmas T, Hirvonen A, Leino-Arjas P
Abstract excerpt
OBJECTIVES: Available evidence suggests that genetic factors and overweight play major roles in the aetiology of osteoarthritis (OA). We analysed the association of 18 single-nucleotide polymorphisms (SNPs) from nine adipokine and adipokine receptor genes (LEP, LEPR, ADIPOQ, RETN, NAMPT, SERPINA12, ITLN1, RARRES2, and APLN) with radiographic hand OA. METHOD: The study design was cross-sectional. Bilateral hand...
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