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Article

Estrogen receptor gene polymorphism and generalized osteoarthritis.

The Journal of rheumatology - 1 Jan 1998

Ushiyama T, Ueyama H, Inoue K, Nishioka J, Ohkubo I, Hukuda S

Abstract excerpt

OBJECTIVE: Generalized osteoarthritis (OA) is a common disease, more often affecting women than men. Although genetic factors are known to be the major risk factor, the genes related to its development are as yet undetermined. We investigated the association between estrogen receptor gene polymorphisms and generalized OA. METHODS: Pvu II and Xba I restriction fragment length polymorphisms (RFLP) of estrogen...

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PMID: 9458216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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