Article
The Kinesin motor protein Cut7 regulates biogenesis and function of Ago1-complexes.
Traffic (Copenhagen, Denmark) - 1 Jan 2010
Stoica Cezar, Park Jungsook, Pare Justin M, Willows Steven, Hobman Tom C
Abstract excerpt
Argonaute proteins are the effectors of small RNA-dependent gene-silencing pathways. In the cytoplasm, they are incorporated into large mobile ribonucleoprotein (RNP) complexes that travel along microtubules. We used a genetic screen to identify the microtubule-associated motor that interacts with Ago1-containing RNPs. Here, we report that activity of the kinesin family member Cut7 is important for biogenesis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
