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Article

Widespread translational inhibition by plant miRNAs and siRNAs.

Science (New York, N.Y.) - 30 May 2008

Brodersen Peter, Sakvarelidze-Achard Lali, Bruun-Rasmussen Marianne, Dunoyer Patrice, Yamamoto Yoshiharu Y, Sieburth Leslie, Voinnet Olivier

Abstract excerpt

High complementarity between plant microRNAs (miRNAs) and their messenger RNA targets is thought to cause silencing, prevalently by endonucleolytic cleavage. We have isolated Arabidopsis mutants defective in miRNA action. Their analysis provides evidence that plant miRNA-guided silencing has a widespread translational inhibitory component that is genetically separable from endonucleolytic cleavage. We further...

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PMID: 18483398
DOI: 10.1126/science.1159151

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AGO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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