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Article

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.

Molecular biology of the cell - 1 Jul 2005

Zhu Changjun, Zhao Jian, Bibikova Marina, Leverson Joel D, Bossy-Wetzel Ella, Fan Jian-Bing, Abraham Robert T, Jiang Wei

Abstract excerpt

Microtubule (MT)-based motor proteins, kinesins and dyneins, play important roles in multiple cellular processes including cell division. In this study, we describe the generation and use of an Escherichia coli RNase III-prepared human kinesin/dynein esiRNA library to systematically analyze the functions of all human kinesin/dynein MT motor proteins. Our results indicate that at least 12 kinesins are involved in...

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Identifiers

PMID: 15843429
DOI: 10.1091/mbc.e05-02-0167
PMCID: PMC1165403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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